Accelerating and Enhancing the Drug Discovery Process
“Accelerating and Enhancing the Drug Discovery Process”
Richard A. Houghten, Ph.D.
Founder, CEO & President, Torrey Pines Institute for Molecular Studies
Dr. Houghten's seminar will be cosponsored by Department of Chemistry & Biochemistry, College of Medicine, and the Biomolecular Sciences Institute.
Time: Friday November 22, 11 am
Location: College of Business Complex Room 155 (CBC-155) – MMC (live) Marine Sciences Building Room 105 (MSB-105) – BBC (via polycom)
Sponsored by the Department of Chemistry & Biochemistry, the Biomolecular Sciences Institute and the Herbert Wertheim College of Medicine.
Torrey Pines Institute has generated very large mixture-based combinatorial libraries that allow for high throughput screening of millions of compounds. Screening methods using disease-relevant animal models being developed at Torrey Pines Institute have the potential to revolutionize drug discovery by identifying individual compounds that are inherently more translatable to human diseases as well as identify compounds that are efficacious through previous unknown biological mechanisms or through multiple biological pathways. Dr. Houghten will describe the concepts of how the Torrey Pines libraries are synthesized, screened and deconvoluted to identify individual compounds.